Many methods of intradermal hyposensitization with insulin (in fact, immunization with insulin) have been proposed, largely differing in the rate of increasing the intradermal dose of insulin.


The rate of hyposensitization in the case of severe allergic reactions of the immediate type is determined primarily by the body's response to an increase in the dose of insulin.

  • Sometimes it is suggested to start with very high, almost homeopathic, dilutions (1:100,000, for example).
  • Desensitization techniques used today in the treatment of allergy to human insulin preparations and human insulin analogs have been described for a long time, including in my doctoral dissertation, which presents the results of my treatment of about 50 cases of a severe allergic reaction of an immediate type to all insulin preparations produced at that time.
  • Treatment is extremely burdensome for both the patient and the doctor, sometimes dragging on for several months.
"After that meeting I wrote to Alena Sinkevich, she's an employee of the "Volunteers to help orphans," Nadezhda continues. - It was Alena who collected money for Lekha's surgery and communicated with him a lot. I had a lot of questions for her. How do people like Lekha live? What awaits him? How to take care of him, is it possible to teach him? But Alyona knew very little, as, in fact, all our doctors do. She just said that somehow Lekha lives, that he is very kind, intelligent and loves people. And that he was born to be in a family.

Alyona was on the board of trustees of the orphanage where Lesha lived. And she liked the boy immediately. According to her, Lesha gave off a vibe of love and empathy. He was giving them out into the space, like a router gives out the Internet. The boy was sociable, and if someone started talking to him, he would literally shake with joy.